Changelog
2020 Jul 13
- Updated the database to represent the latest UniProt release
- Fixed a bug when UniProt Entry inputs were not treated correctly
2018 Dec 17
- Major ANCHOR2 rework
- Reverted the change introduced at Jul 13, ANCHOR2 now produces identical output to original publication
- Major REDOX prediction rework
- Redox prediction was changed in multiple ways. For details see:
Large-scale analysis of redox-sensitive conditionally disordered protein regions reveals their widespread nature and key roles in high-level eukaryotic processesGabor Erdos, Balint Meszaros, Dana Reichmann, Zsuzsanna DosztanyiPROTEOMICS, in press
- Added an option to Download page to download the Redox predictor
2018 Sep 3
- Fixed a bug about glob mode producing errors when no globular region is found
2018 Jul 13
- Major ANCHOR2 rework
- Removed the IUPred2 smoothing step from ANCHOR2
- Lowercase amino acid sequence input is now processed correctly
2018 Jul 10
- Fixed a bug when text based output was not displaying the given protein
2018 Jun 12
- Fixed a bug when REST interface was not producing output
References
Primary citations
Bálint Mészáros, Gábor Erdős, Zsuzsanna Dosztányi
IUPred2A: context-dependent prediction of protein disorder as a function of redox state and protein binding
Nucleic Acids Research 2018;46(W1):W329-W337.
Gábor Erdős, Zsuzsanna Dosztányi
Analyzing Protein Disorder with IUPred2A
Current Protocols in Bioinformatics 2020;70(1):e99
Additional citations
Zsuzsanna Dosztányi
Prediction of protein disorder based on IUPred
Protein Science 2017;27:331-340.
Dosztányi Z, Csizmók V, Tompa P, Simon I.
The pairwise energy content estimated from amino acid composition discriminates between folded and intrinsically unstructured proteins
J Mol Biol. 2005;347:827-39.
Mészáros B, Simon I, Dosztányi Z.
Prediction of protein binding regions in disordered proteins
PLoS Comput Biol. 2009;5:e1000376.
Bálint Mészáros, Gábor Erdős, Zsuzsanna Dosztányi
IUPred2A: context-dependent prediction of protein disorder as a function of redox state and protein binding
Nucleic Acids Research 2018;46(W1):W329-W337.
Gábor Erdős, Zsuzsanna Dosztányi
Analyzing Protein Disorder with IUPred2A
Current Protocols in Bioinformatics 2020;70(1):e99
Additional citations
Zsuzsanna Dosztányi
Prediction of protein disorder based on IUPred
Protein Science 2017;27:331-340.
Dosztányi Z, Csizmók V, Tompa P, Simon I.
The pairwise energy content estimated from amino acid composition discriminates between folded and intrinsically unstructured proteins
J Mol Biol. 2005;347:827-39.
Mészáros B, Simon I, Dosztányi Z.
Prediction of protein binding regions in disordered proteins
PLoS Comput Biol. 2009;5:e1000376.