Intrinsically disordered proteins (IDPs) have no single well-defined tertiary structure
under native
conditions. IUPred2A is a combined web interface that allows to identify disordered
protein
regions
using IUPred2 and disordered binding regions using ANCHOR2. IUPred2A is also capable of
identifying
protein regions that do or do not adopt a stable structure depending on the redox state
of
their
environment. IUPred2A supersedes the previous
IUPred and
ANCHOR servers. For new features
included in IUPred2A, see the
New features
section.
For a detailed description of how to run IUPred2A using various features and how to
interpret the output,
see the
How to use and
Examples sections. For a simple demonstration of how
to
input data, see the
example 1 or
example 2.